Mouthwashes could reduce the risk of coronavirus transmission, new study reveals. They could also help reduce the viral load of SARS-CoV-2 over the short term SARS-CoV-2 viruses can be inactivated using certain commercially available mouthwashes. A team of virologists demonstrated the discovery in cell culture. The use of mouthwashes that are effective against SARS-CoV-2 could help to reduce the viral load the transmission over the short term. This could be beneficial when visiting the dentist. For the study, researchers tested 8 types of mouthwash with different ingredients that are commercially available in pharmacies in Germany.
First, researches mixed each mouthwash with virus particles and an interfering substance. The interfering substance recreates the effect of saliva in the mouth. The mixed was then shaken for 30 seconds to simulate the impact of gargling. They then used Vero E6 cells to determine the virus concentration Vero E6 cells are particularly receptive to SARS-CoV-2. Researchers assessed the efficacy of the mouthwashes. So they treated the virus suspensions with cell culture medium instead of the mouthwash. Researchers finally added the mix to the cell culture.
All of the tested preparations reduced the initial virus concentration. Three types of mouthwash eliminated the virus after an exposure time of 30 seconds. Researchers noted that mouth rinses cannot treat COVID-19 infections. They also cannot protect people against catching the virus. Gargling with mouthwash cannot inhibit the production of viruses in the cells. But it could reduce the viral load in the short term especially in the highly-critical oral cavity and throat.
Oral rising might reduce the viral load of saliva. Which could ultimately lead to lower transmission of SARS-CoV-2. Further studies are needed to determine whether this effect is confirmed in clinical practice and how long this effect can last. The team is exploring the possibility of a clinical study on the efficacy of mouthwashes on SARS-CoV-2. The goal of this study is to test whether the effect can also be detected in patients